Sub-lethal Ocular Trauma (SLOT): Establishing a Standardized Blast Threshold to Facilitate Diagnostic, Early Treatment, and Recovery Studies for Blast Injuries to the Eye and Optic Nerve
Annual rept. 15 Aug 2012-15 Aug 2013
TEXAS UNIV AT SAN ANTONIO
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The report summarizes the results of tasks undertaken during Year 1 of the project Sub-lethal Ocular Trauma SLOT Establishing a Standardized Blast Threshold to Facilitate Diagnostic, Early Treatment, and Recovery Studies for Blast Injuries to the Eye and Optic Nerve. The 3 year effort aims to fill a gap in our understanding of physical mechanisms and progression of primary blast-induced ocular injury. A fully-integrated experimental and computational study was undertaken. Primary blast experiments were conducted using a large diameter shock tube and ex vivo porcine eye specimens. The experiments were supported by numerical modeling using physics-based codes CTH and LS-DYNA. Post-blast evaluation of eye specimens using UBM and B-scan, as well as gross dissection and detailed histopathology, allowed for preliminary development of trauma risk curves for a number of sub-globe-rupture trauma categories. The data generated in this study has increased our understanding of primary blast-induced ocular trauma. The shock tube produced a broad array of closed-globe injuries such as angle recession, cyclodialysis, peripheral chorioretinal detachments, radial peripapillary retinal detachments, and internal scleral delaminations. Development of a rigorous experimental methodology and use of pre-blast ultrasound screening gave confidence that the observed injuries were due to the effects of primary blast.
- Anatomy and Physiology
- Medicine and Medical Research
- Weapons Effects (Biological)