Accession Number:

ADA610706

Title:

Evaluation of Diffusion Kurtosis Imaging in Traumatic Brain Injury

Descriptive Note:

Annual rept. 2 Apr 2012-1 Apr 2013

Corporate Author:

MARYLAND UNIV BALTIMORE

Personal Author(s):

Report Date:

2013-05-01

Pagination or Media Count:

20.0

Abstract:

The goal of this study is to identify novel imaging marker such as diffusion kurtosis that may serve as a prognostic marker in the evaluation and management of traumatic brain injury patients. This study will recruit patients patients with varying severity of traumatic brain injury mild, moderate, severe from the Shock Trauma center with an initial diagnosis of diffuse axonal injury. Neuropsychological testing and magnetic resonance imaging will be performed in the acute, sub-acute and chronic stages through 6 months. The relationship between the advanced magnetic resonance imaging markers and the clinical condition of the patient will be evaluated at each time point to determine which of the imaging markers, or a combination of imaging markers are best representative of the clinical condition of the patient. Further, the markers will be evaluated for their prognostic ability to determine the clinical course of the TBI patients.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE