Synthesis of C13- and N15-Labeled DNAN
NAVAL SURFACE WARFARE CENTER INDIAN HEAD DIV MD EXPLOSIVE ORDNANCE DISPOSAL TECHNOLOGY DIV
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Isotopically labeled C13 and N15 and unlabeled DNAN were synthesized in two steps from chlorobenzene in high purity and regioselectivity with an overall yield of 69 from readily available materials. The syntheses and full characterizations H1, C13, N14, N15 NMR, IR, and HRMS of labeled and unlabeled DNAN, as well as its synthetic precursor, 1-chloro-2,4-dinitrobenzene, are discussed. The use of isotopically labeled material and their spectra will enable the toxicity and biodegradation potential of DNAN to be more easily determined.
- Organic Chemistry
- Ammunition and Explosives