Accession Number:

ADA609479

Title:

Noninvasive MR-Guided HIFU Therapy of TSC-Associated Renal Angiomyolipomas

Descriptive Note:

Final rept. 1 Jul 2011-30 Jun 2014

Corporate Author:

CHILDREN'S HOSPITAL CINCINNATI OH

Personal Author(s):

Report Date:

2014-09-01

Pagination or Media Count:

14.0

Abstract:

This report is a summary of our three years work on the proposed research. During this period, our effort was focused on technological development for thermal ablation in animals. We have established an MR-guided HIFU experimental system that enables simultaneous HIFU ablation and MR guidance in a physiological environment. However, it was found in our in vivo experiments that the established system is more suitable for large-animal models. As a result, mouse tumor ablation cannot be implemented in our studies. Based on this investigation, we are reformatting our research and planning for another effort to investigate MR-guided HIFU therapy of TSC-related renal angiomyolipomas in large animal models.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE