Accession Number:

ADA609248

Title:

Characterization of Nanoparticles by Capillary Electrophoresis and Trapping of Nanoparticles in Microfluidics Device

Descriptive Note:

Contract rept.

Corporate Author:

CANADA WEST BIOSCIENCES CALGARY (ALBERTA)

Report Date:

2009-08-01

Pagination or Media Count:

34.0

Abstract:

The contractor report describes research performed for Contract No. W7702-04R-021. The work was carried out in support of CRTI 03-005RD. The report describes the use of capillary electrophoresis CE as an analytical method for characterizing gold, polymer and iron oxide nanoparticles NPs. The analyte species were detected by UVvis or laser-induced fluorescence LIF spectroscopy. For analytes that possessed neither UVvis absorbance nor LIF, indirect methods of detection were employed whereby a signal-generating molecular species was added to the running buffer. NPs from a variety of commercial sources and from custom syntheses were studied. The report demonstrates that CE is a valuable tool in NP research. The report also demonstrates the feasibility of trapping nanoparticles in microfluidic devices for sample clean up and detection.

Subject Categories:

  • Physical Chemistry
  • Radiation and Nuclear Chemistry
  • Fluidics and Fluerics
  • Electricity and Magnetism

Distribution Statement:

APPROVED FOR PUBLIC RELEASE