In Vitro Osteoblast Model for Bone Wound Infections and Antimicrobial Therapy
Addendum to Final rept. 1 Dec 2011-31 Dec 2012
GENEVA FOUNDATION TACOMA WA
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The developmental processes for bone tissue is complex and involves several tightly regulated gene expression patterns of bone associated proteins. The expression of these genes and proteins are regulated in a temporal manner both in vivo and in vitro and has previously been studied in both these systems. The process of osteoblast differentiation can be subdivided into 3 stages, namely, proliferation, extracellular matrix synthesis and maturation and, lastly, mineralization.
- Anatomy and Physiology
- Medicine and Medical Research