Accession Number:

ADA608594

Title:

In Vitro Osteoblast Model for Bone Wound Infections and Antimicrobial Therapy

Descriptive Note:

Addendum to Final rept. 1 Dec 2011-31 Dec 2012

Corporate Author:

GENEVA FOUNDATION TACOMA WA

Personal Author(s):

Report Date:

2013-01-01

Pagination or Media Count:

40.0

Abstract:

The developmental processes for bone tissue is complex and involves several tightly regulated gene expression patterns of bone associated proteins. The expression of these genes and proteins are regulated in a temporal manner both in vivo and in vitro and has previously been studied in both these systems. The process of osteoblast differentiation can be subdivided into 3 stages, namely, proliferation, extracellular matrix synthesis and maturation and, lastly, mineralization.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE