Acute Dermal Irritation Study of Six Jet Fuels in New Zealand White Rabbits: Comparison of Four Bio-Based Jet Fuels with Two Petroleum JP-8 Fuels
Interim rept. Jun 2013-Jan 2014
HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE WRIGHT-PATTERSON AFB OH
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The objective of this study was to determine the irritative potential of two petroleum derived operational jet fuels and four alternative fuels following a single exposure to the skin of New Zealand White rabbits. Operational fuels included two JP-8 formulations JP-8 containing 21.25 mass percent aromatic components as a baseline control for the study and a second high aromatic HA JP-8 containing 28.05 mass percent aromatics for comparison with higher aromatic alternative fuels. The alternative fuels assessed were KiOR hydroprocessed depolymerized cellulosic jet HDCJ fuel ReadiJet fuel produced by Applied Research Associates Amyris C15 Direct Sugar to Hydrocarbon DSHC and Virent Synthetic Aromatic Kerosene SAK. There were no significant differences in irritation noted between the baseline fuels JP-8 and HA JP-8 and the four alternate jet fuels all were slightly irritating when exposed under occluded and semi-occluded conditions, with the exception of ReadiJet which was nonirritating when exposed semi-occluded. It is not expected that normal handling of these fuels would result in increased dermal irritation among airmen.