Accession Number:

ADA602709

Title:

Novel Electromagnetic - Ultrasound Synergistic Technique for Treatment of Cancer

Descriptive Note:

Final rept. 1 Sep 2010-31 Aug 2013

Corporate Author:

MICHIGAN UNIV ANN ARBOR

Report Date:

2013-11-01

Pagination or Media Count:

66.0

Abstract:

Hyperthermia and thermal ablation are thermal therapies in which the cytotoxic effects of elevated temperatures in tissue are induced to achieve cell death or render the cells more vulnerable to ionizing radiation and chemical toxins. In application of a thermal ablation approach, high intensity focused ultrasound HIFU and high intensity focused microwave HIFW have been explored for various medical conditions. Our research is primarily directed at addressing severe limitations of HIFU, that is, very slow treatment times for large, deep lesions, including those close to the chest wall, by combining HIFU and HIFW, and in each modality, introducing new techniques that substantially enhance the treatment results. Two modalities will capitalize on the advantages of each in various situations, and will allow comparison of those advantages as the research progresses to in vivo studies. In this collaborative research, work between the Microwave and Ultrasound groups is being conducted to develop a technique that will synergize the fast heat delivery properties of microwaves with high spatial resolution of ultrasound. This particular progress report is for the ultrasound portion and its future integration with the microwave system.

Subject Categories:

  • Radiobiology
  • Toxicology
  • Radio Communications

Distribution Statement:

APPROVED FOR PUBLIC RELEASE