Accession Number:

ADA596945

Title:

Core Modular Blood and Brain Biomarkers in Social Defeat Mouse Model for Post Traumatic Stress Disorder

Descriptive Note:

Corporate Author:

CALIFORNIA UNIV SANTA BARBARA

Personal Author(s):

• Yang, Ruoting
• Daigle, Jr, Bernie J.
• Muhie, Seid Y.
• Hammamieh, Rasha
• Jett, Marti
• Petzold, Linda
• Doyle, III, Francis J.

Report Date:

2013-08-20

Pagination or Media Count:

27.0

Abstract:

Post-traumatic stress disorder PTSD is a severe anxiety disorder that affects a substantial portion of combat veterans and poses serious consequences to long-term health. Consequently, the identification of diagnostic and prognostic blood biomarkers for PTSD is of great interest. Previously, we assessed genome-wide gene expression of seven brain regions and whole blood in a social defeat mouse model subjected to various stress conditions.

Descriptors:

• *POST TRAUMATIC STRESS DISORDER
• ANXIETY
• BLOOD
• BRAIN
• CORES
• ORDER DISORDER TRANSFORMATIONS
• STRESS(PHYSIOLOGY)

Subject Categories:

• Anatomy and Physiology
• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE