Hydroprocessed Esters and Fatty Acids (HEFA) Bio-Based Jet Fuels: Sensory Irritation Study and Human Health Hazard Assessment
Interim rept. Jan 2011-Jun 2012
AIR FORCE RESEARCH LAB BROOKS CITY BASE TX HUMAN EFFECTIVENESS DIRECTORATE DIRECTED ENERGY BIOEFFECTS DIVISION/ OPTICAL RADIATION BRANCH
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The purpose of this technical report is two-fold. First, this technical report presents the results of a sensory irritation assay conducted in male Swiss-Webster mice exposed to different concentrations of hydroprocessed esters and fatty acids HEFA bio-based jet fuels, HEFA-Camelina HEFA-C and HEFA-Tallow HEFA-T. The mice were exposed via a modified nose-only plethysmograph tube to each fuel, administered as an aerosolvapor combination. For HEFA-C, the predicted RD50 50 percent reduction in respiratory rate was greater than 11,755 mgm3. For HEFA-T, the predicted RD50 was greater than 13,306 mgm3. This technical report also summarizes toxicity data for HEFA fuels, including HEFA-C, HEFA-T and a HEFA fuel with a feedstock of mixed animal fats and oils HEFA-F. HEFA toxicity data are then compared with toxicity data from synthetic paraffinic kerosene SPK alternative jet fuel and petroleum derived JP-8. The toxicity data are used to develop a comparative occupational exposure limit OEL for HEFA fuels that concurs with the current JP-8 OEL 200 mgm3.
- Anatomy and Physiology