Accession Number:

ADA592834

Title:

Biomarkers for Autism and for Gastrointestinal and Sleep Problems in Autism

Descriptive Note:

Revised annual rept.

Corporate Author:

YALE UNIV NEW HAVEN CT

Personal Author(s):

Report Date:

2013-10-01

Pagination or Media Count:

4.0

Abstract:

The study is still collecting specimens. No interim data analysis has been performed at this point. As specified in the EWOF request, data analysis will begin on or about June 1, 2014. The objective of the proposed research is to compare the production of melatonin by young children with autism N45 to typically developing children N45. Specifically, we will see if the nighttime excretion rate of melatonin sulfate is markedly lower in the children with autism, whether there is a subgroup of children with autism having very low excretion whether low nighttime excretion of melatonin sulfate is associated with sleep problems and whether low daytime melatonin sulfate excretion is associated with gastrointestinal problems.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE