Deciphering the Translational Determinants of Prostate Cancer Initiation and Progression
Andrew summary rept. 1 Jul 2011-30 Jun 2012
CALIFORNIA UNIV SAN FRANCISCO
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My work is focused on determining the molecular mechanism by which aberrant translational control downstream oncogenic PI3K-AKT-mTOR signaling causes and drives prostate cancer progression. The goal of this work is to provide the mechanistic rationale for using novel second-generation mTOR inhibitors in the clinic for the alleviation of human suffering and death from mTOR driven malignancies.
- Medicine and Medical Research