Accession Number:

ADA591656

Title:

Deciphering the Translational Determinants of Prostate Cancer Initiation and Progression

Descriptive Note:

Andrew summary rept. 1 Jul 2011-30 Jun 2012

Corporate Author:

CALIFORNIA UNIV SAN FRANCISCO

Personal Author(s):

Report Date:

2012-07-01

Pagination or Media Count:

27.0

Abstract:

My work is focused on determining the molecular mechanism by which aberrant translational control downstream oncogenic PI3K-AKT-mTOR signaling causes and drives prostate cancer progression. The goal of this work is to provide the mechanistic rationale for using novel second-generation mTOR inhibitors in the clinic for the alleviation of human suffering and death from mTOR driven malignancies.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE