Chemotherapy Necessitates Increased Immune Control of HHVs: A Cause of Persistent Inflammation Enabling Protracted Fatigue in Breast Cancer Survivors
Annual summary rept. 15 Sep 2012-14 Sep 2013
MEDICAL UNIV OF SOUTH CAROLINA CHARLESTON
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The purpose of this work is to determine the incidence rate and relative risk in women who have undergone chemotherapy and have a high HHV load toward severe CTRF. We aim to determine whether immune cell burden induced by viral surveillance leads to severe fatigue in these retrospective and prospective cohorts. The progress of the past year of this award was dedicated to finding a university where the PI had a solid program and mentorship committee that supports the advancement of the PI and the research proposed here. Furthermore, as these data are collected over the next year, Medical University of South Carolina offers a dedicated and experienced team of breast cancer doctors and researchers who support the initial scope of this project and possess the capacity and resources to expand upon finding from these studies toward an ultimate goal of improved post-chemotherapy quality of life for breast cancer survivors.
- Medicine and Medical Research