Accession Number:

ADA591377

Title:

Prevention of Stimulant Induced Euphoria with an Opioid Receptor Antagonist

Descriptive Note:

Annual rept. 30 Sep 2012-29 Sep 2013

Corporate Author:

MASSACHUSETTS GENERAL HOSPITAL BOSTON

Personal Author(s):

Report Date:

2013-10-01

Pagination or Media Count:

19.0

Abstract:

The protocol, sponsored by the Department of Defense, is a 6-week study examining whether Methylphenidate-induced euphoria can be attenuated by co-administration with Naltrexone In medication native young adults age 18-30 with a euphoric response to MPH administered on the Drug Feeling visit. In this double bind study, subjects will receive MPH and Naltrexone or a placebo to treat their ADHD symptoms over the course of the 6-week trial.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE