Prevention of Stimulant Induced Euphoria with an Opioid Receptor Antagonist
Annual rept. 30 Sep 2012-29 Sep 2013
MASSACHUSETTS GENERAL HOSPITAL BOSTON
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The protocol, sponsored by the Department of Defense, is a 6-week study examining whether Methylphenidate-induced euphoria can be attenuated by co-administration with Naltrexone In medication native young adults age 18-30 with a euphoric response to MPH administered on the Drug Feeling visit. In this double bind study, subjects will receive MPH and Naltrexone or a placebo to treat their ADHD symptoms over the course of the 6-week trial.
- Anatomy and Physiology
- Medicine and Medical Research
- Stress Physiology