Vitamin D for Cancer Prevention: Global Perspective
NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA
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The papers in this review support a role of vitamin D repletion in reducing incidence of cancer. Higher levels of the main circulating form of vitamin D, 25-hydroxyvitamin D 25OHD, were associated with lower risk of colon, breast, and ovarian cancer. There was a linear dose-response gradient above an approximately 25 ngml threshold, with few exceptions. Action is needed by public health officials and professional and voluntary organizations to recommend universal intake of 2,000 IUday of vitamin D3 with a suitable dietary intake of calcium in populations residing at 30 deg. from the equator, starting at age 1 year. The evidence reviewed here indicates that such action will rapidly prevent a substantial proportion of cases and deaths from breast, colon, ovarian, and other cancers.
- Medicine and Medical Research
- Food, Food Service and Nutrition