Accession Number:

ADA582846

Title:

Plasma-Enhanced Copolymerization of Amino Acid and Synthetic Monomers

Descriptive Note:

Journal article

Corporate Author:

GEORGIA INST OF TECH ATLANTA SCHOOL OF MATERIALS SCIENCE AND ENGINEERING

Report Date:

2011-12-16

Pagination or Media Count:

14.0

Abstract:

In this paper we report the use of plasma-enhanced chemical vapor deposition PECVD for the simultaneous deposition and copolymerization of an amino acid with other organic and inorganic monomers. We investigate the fundamental effects of plasma-enhanced copolymerization on different material chemistries in stable ultrathin coatings of mixed composition with an amino acid component. This study serves to determine the feasibility of a direct, facile method for integrating biocompatibleactive materials into robust polymerized coatings with the ability to plasma copolymerize a biological molecule L-tyrosine with different synthetic materials in a dry, one-step process to form ultrathin coatings of mixed composition. This process may lead to a method of interfacing biologic systems with synthetic materials as a way to enhance the biomaterial-tissue interface and preserve biological activity within composite films.

Subject Categories:

  • Biochemistry
  • Organic Chemistry
  • Polymer Chemistry
  • Plastics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE