Accession Number:

ADA582846

Title:

Plasma-Enhanced Copolymerization of Amino Acid and Synthetic Monomers

Descriptive Note:

Journal article

Corporate Author:

GEORGIA INST OF TECH ATLANTA SCHOOL OF MATERIALS SCIENCE AND ENGINEERING

Personal Author(s):

• Anderson, Kyle D.
• Young, Seth L.
• Jiang, Hao
• Jakubiak, Rachel
• Bunning, Timothy J.
• Naik, Rajesh R.
• Tsukruk, Vladimir V.

Report Date:

2011-12-16

Pagination or Media Count:

14.0

Abstract:

In this paper we report the use of plasma-enhanced chemical vapor deposition PECVD for the simultaneous deposition and copolymerization of an amino acid with other organic and inorganic monomers. We investigate the fundamental effects of plasma-enhanced copolymerization on different material chemistries in stable ultrathin coatings of mixed composition with an amino acid component. This study serves to determine the feasibility of a direct, facile method for integrating biocompatibleactive materials into robust polymerized coatings with the ability to plasma copolymerize a biological molecule L-tyrosine with different synthetic materials in a dry, one-step process to form ultrathin coatings of mixed composition. This process may lead to a method of interfacing biologic systems with synthetic materials as a way to enhance the biomaterial-tissue interface and preserve biological activity within composite films.

Descriptors:

• *AMINO ACIDS
• *COPOLYMERIZATION
• *MONOMERS
• *SYNTHETIC MATERIALS
• BIOLOGY
• CHEMICAL VAPOR DEPOSITION

Subject Categories:

• Biochemistry
• Organic Chemistry
• Polymer Chemistry
• Plastics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE