Accession Number:

ADA582484

Title:

Simulated Optimization of Brachytherapy for the Treatment of Breast Cancer

Descriptive Note:

Revised annual summary rept. 15 Dec 2011-14 Dec 2012

Corporate Author:

CALIFORNIA UNIV SAN DIEGO LA JOLLA

Personal Author(s):

• Graf, Miriam

Report Date:

2013-01-01

Pagination or Media Count:

12.0

Abstract:

This project s dual objectives are the preparation of the PI for a career in breast cancer research and the design of a system of computer-base simulations capable of evaluating the effectiveness of various methods of breast cancer brachytherapy treatments both in general and for each individual patient for use in clinical decision-making. PI was trained in the use of the ABAQUS software package to finish the Finite Element portion of the project as well as acquiring additional computing resources to facilitate and streamline the remaining parts of the project. Using these resources, models of the various treatment devices were created with manufacturer specifications and tested in an idealized tissue model of a breast demonstrating adequate similarity to documented physical behavior. Work was then started on creating breast models from patient data to reflect geometry and approximate tissue inhomogeneity. This work is still in progress.

Descriptors:

• *BREAST CANCER
• *MEDICAL RESEARCH
• COMPUTER PROGRAMS
• DECISION MAKING
• FINITE ELEMENT ANALYSIS
• GEOMETRY
• MAMMARY GLANDS
• MONTE CARLO METHOD
• PATIENTS
• PHYSICAL PROPERTIES
• RADIATION
• SPECIFICATIONS

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE