Accession Number:

ADA582063

Title:

Veno-venous Extracorporeal CO2 Removal: Can We Reduce Dependence on Mechanical Ventilation During En-route Care?

Descriptive Note:

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

2010-04-01

Pagination or Media Count:

13.0

Abstract:

Casualties with lung failure are mechanically ventilated during aero-medical evacuation to the continental USA. Positive-pressure mechanical ventilation is potentially injurious to the lung. Consequences of contemporary lung-protective strategies may include cardiovascular instability, use of high fraction of inspired O2, hypoventilation, hypercarbia, and acidosis. These effects may complicate patient management, motivating a search for better lung-replacement approaches. We investigated the ability of a novel extracorporeal veno-venous CO2 removal V2CO2R device to reduce minute ventilation MV while maintaining normocarbia. Our goal was to explore the potential utility of this technology to reduce dependence on mechanical ventilation during en-route care.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research
  • Medical Facilities, Equipment and Supplies

Distribution Statement:

APPROVED FOR PUBLIC RELEASE