Accession Number:

ADA581255

Title:

Synthesis and Characterization of Antimicrobial Nanomaterials

Descriptive Note:

Final rept. 10 Apr 2006-31 Dec 2012

Corporate Author:

UNIVERSAL TECHNOLOGY CORP DAYTON OH

Personal Author(s):

• Luckarift, Heather R.
• Eby, D. M.
• Farrington, Karen E.
• Tatum, Randi N.
• Johnson, Glenn R.

Report Date:

2013-01-01

Pagination or Media Count:

21.0

Abstract:

The work describes how understanding fundamental biological and biophysical phenomena can be used to develop rational biotechnology solutions for Air Force requirements. Particular emphasis throughout is the integration of catalytically active biomolecules with support matrices and the utilization of these hybrid materials for development of decontamination treatments and self-sanitizing materials. Specific objectives are i to understand the relationship between protein template molecules and metal-oxide nanoparticles, ii define the bacteriolytic mechanism for enzymes immobilized in metal-oxide nanoparticles and iii to evaluate antimicrobial activity from combinations of bacteriolytic hydrolases and antimicrobial peptides.

Descriptors:

• *BIOMOLECULES
• COMPOSITE MATERIALS
• DECONTAMINATION
• IMMUNITY
• NANOPARTICLES
• PEPTIDES

Subject Categories:

• Biochemistry
• Laminates and Composite Materials

Distribution Statement:

APPROVED FOR PUBLIC RELEASE