Accession Number:

ADA574471

Title:

Emergency Preservation and Resuscitation for Cardiac Arrest from Trauma (EPR-CAT)

Descriptive Note:

Annual rept. 26 Sep 2010-25 Sep 2011

Corporate Author:

PITTSBURGH UNIV PA

Personal Author(s):

Report Date:

2012-10-01

Pagination or Media Count:

6.0

Abstract:

Cardiopulmonary resuscitation CPR can save victims of normovolemic cardiac arrest CA, e.g., ventricular fibrillation. During exsanguination CA from trauma, however, CPR, even with an emergency department ED thoracotomy and open chest CPR, doesn t work. Emergency Preservation and Resuscitation EPR was developed to rapidly preserve the organism during ischemia, using hypothermia, drugs, and fluids, to buy time for transport and resuscitative surgery. The purpose of this study is to test the feasibility of rapidly inducing profound hypothermia 10oC with an aortic flush in trauma victims that have suffered CA and failed standard resuscitative efforts to enable resuscitative surgery and delayed resuscitation with cardiopulmonary bypass. The primary outcome variable will be survival to hospital discharge with minimal neurologic dysfunction.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE