Improvements in Diagnostic Accuracy with Quantitative Dynamic Contrast Enhanced MRI
Annual rept. 1 Dec 2011- 30 Nov 2012
CHICAGO UNIV IL
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We have continued scanning patients with the calibration phantoms and a research scanning protocol that allows us to acquire quantitative images of the breast displaying concentration of contrast media. These data can be used to generate maps displaying different parameters descriptive of contrast uptake, and pharmacokinetics, which are diagnostically useful. A subset of patients has been scanned at two field strengths 1.5T and 3T. Analysis of these data indicates a reduction in the variation across the scans with the quantitative methods proposed. By analyzing the sources of variability in the quantitative results, we aim to reduce differences across different fields even more. To date, 32 patients have been scanned with the calibration phantoms, 11 of them at two field strengths. Recruitment is ongoing, as well as refinement of our methods in order to increase their reliability.
- Medicine and Medical Research