Accession Number:

ADA574372

Title:

Improvements in Diagnostic Accuracy with Quantitative Dynamic Contrast Enhanced MRI

Descriptive Note:

Annual rept. 1 Dec 2011- 30 Nov 2012

Corporate Author:

CHICAGO UNIV IL

Personal Author(s):

Report Date:

2012-12-01

Pagination or Media Count:

14.0

Abstract:

We have continued scanning patients with the calibration phantoms and a research scanning protocol that allows us to acquire quantitative images of the breast displaying concentration of contrast media. These data can be used to generate maps displaying different parameters descriptive of contrast uptake, and pharmacokinetics, which are diagnostically useful. A subset of patients has been scanned at two field strengths 1.5T and 3T. Analysis of these data indicates a reduction in the variation across the scans with the quantitative methods proposed. By analyzing the sources of variability in the quantitative results, we aim to reduce differences across different fields even more. To date, 32 patients have been scanned with the calibration phantoms, 11 of them at two field strengths. Recruitment is ongoing, as well as refinement of our methods in order to increase their reliability.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE