Investigations of Tissue-Level Mechanisms of Primary Blast Injury Through Modeling, Simulation, Neuroimaging and Neuropathological Studies
Final rept. 1 Aug 2011-14 Nov 2012
MASSACHUSETTS INST OF TECH CAMBRIDGE
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Traumatic brain injury TBI to U.S. soldiers has become one of the most taxing consequences of IED attacks in OEFOIF. This project has focused on investigations of traumatic injury to the brain caused by the primary effects of blast waves. The project combines clinical, experimental and modeling studies aimed at i elucidating the cell and tissue-level mechanisms of injury produced by the effect of the blast wave, ii deriving associated blast injury criteria metrics and thresholds, iii helping to identify and treat returnees suffering from TBI, and iv developing blast protection strategies for TBI mitigation.
- Medicine and Medical Research