Accession Number:

ADA571881

Title:

Human Neural Cell-Based Biosensor

Descriptive Note:

Quarterly technical rept. 1 Oct-31 Dec 2012

Corporate Author:

ARUNA BIOMEDICAL INC ATHENS GA

Personal Author(s):

Report Date:

2012-12-07

Pagination or Media Count:

4.0

Abstract:

Our goal is to provide a more biologically relevant model of human physiology for the purpose of developing in vitro, cell based biosensors for environmental toxins. Specifically we plan to develop human neural based biosensors by using ArunAs neural cell lines derived from both human embryonic stem cells hESCs and human induced pluripotent stem cells hiPSCs. This report describes the progress made in these major areas 1 directed differentiation of hESC- and hiPSC-derived neural progenitor cells into dopaminergic neurons 2 directed differentiation of hESC- and hiPSC-derived neural progenitor cells into astrocytes 3 label-free, adhesive signature-based microfluidic cell separation and 4 neural crest differentiation.

Subject Categories:

  • Chemical, Biological and Radiological Warfare
  • Miscellaneous Detection and Detectors

Distribution Statement:

APPROVED FOR PUBLIC RELEASE