Natural Products as Sources for New Pesticides
AGRICULTURAL RESEARCH SERVICE UNIVERSITY MS NATURAL PRODUCTS UTILIZATION RESEARCH UNIT
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Natural products as pesticides have been reviewed from several perspectives in the past, but no prior treatment has examined the impact of natural product and natural product-based pesticides on the U.S. market, as a function of new active ingredient registrations with the Environmental Protection Agency EPA. Thus, EPA registration details of new active ingredients for all conventional pesticide registrations and biopesticide registrations were compiled from the years 1997 2010. Conventional pesticide registrations and biopesticide registrations were examined both collectively and independently for all 277 new active ingredients NAI and subsequently categorized and sorted into four types biological B, natural product NP, synthetic S, and synthetic natural derived SND. When examining conventional pesticides alone, the S category accounted for the majority of NAI registrations, with 78.0, followed by SND with 14.7, NP with 6.4, and B with 0.9. Biopesticides alone were dominated by NPs with 54.8, followed by B with 44.6, SND with 0.6, and 0 for S. When examining conventional pesticides and biopesticides combined, NPs accounted for the majority of NAI registrations, with 35.7, followed by S with 30.7, B with 27.4, and SND with 6.1. Despite the common perception that natural products may not be the best sources for NAI as pesticides, when both conventional and biopesticides are examined collectively, and considering that NP, SND, and B all have origins from natural product research, it can be argued that their combined impact with the EPA from 1997 to 2010 accounted for 69.3 of all NAI registrations.
- Agricultural Chemistry