Efficacy of Gamma-glutamylcysteine (GGC) in Ischemia-reperfusion Injury
Final rept. 1 Jul 2010-30 Sep 2012
NEVADA SYSTEM OF HIGHER EDUCATION RENO NV
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Hemorrhagic shock is a leading cause of death in military combat and civilian trauma Bellamy, 1984 Lieu, et al., 2004. Better understanding of the associated cellular biochemical changes that occur in ischemia-reperfusion IR injury can lead to efficacious therapies Thomas et al., 2008. Therefore, we have been studying the feasibility of using gamma-glutamylcysteine GGC a dipeptide precursor for glutathione as a potential compound in modulating the oxidative stress associated with IR injury.
- Anatomy and Physiology
- Medicine and Medical Research