Accession Number:

ADA568392

Title:

Efficacy of Gamma-glutamylcysteine (GGC) in Ischemia-reperfusion Injury

Descriptive Note:

Final rept. 1 Jul 2010-30 Sep 2012

Corporate Author:

NEVADA SYSTEM OF HIGHER EDUCATION RENO NV

Personal Author(s):

Report Date:

2012-10-01

Pagination or Media Count:

5.0

Abstract:

Hemorrhagic shock is a leading cause of death in military combat and civilian trauma Bellamy, 1984 Lieu, et al., 2004. Better understanding of the associated cellular biochemical changes that occur in ischemia-reperfusion IR injury can lead to efficacious therapies Thomas et al., 2008. Therefore, we have been studying the feasibility of using gamma-glutamylcysteine GGC a dipeptide precursor for glutathione as a potential compound in modulating the oxidative stress associated with IR injury.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE