Accession Number:

ADA566961

Title:

Lower Prediagnostic Serum 25-Hydroxyvitamin D Concentration Is Associated With Higher Risk of Insulin-requiring Diabetes: A Nested Case-Control Study

Descriptive Note:

Journal article

Corporate Author:

NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA

Personal Author(s):

• Gorham, Edward D.
• Garland, Cedric F.
• Burgi, Alina A.
• Mohr, Sharif B.
• Zeng, Kenneth
• Hofflich, Heather
• Kim, June J.
• Ricordi, Camillo

Report Date:

2012-01-01

Pagination or Media Count:

6.0

Abstract:

Aimshypothesis Low serum 25-hydroxyvitamin D 25 OHD concentration may increase risk of insulinrequiring diabetes. Methods A nested case control study was performed using serum collected during 2002 2008 from military service members. One thousand subjects subsequently developed insulin-requiring diabetes. A healthy control was individually matched to each case on blood-draw date 2 days, age 3 months, length of service 30 days and sex. The median elapsed time between serum collection and first diagnosis of diabetes was 1 year range 1 month to 10 years. Statistical analysis used matched pairs and conditional logistic regression.

Descriptors:

• *BLOOD SERUM
• *DIABETES
• CASE STUDIES
• CONTROL
• HYPOTHESES
• INSULIN
• REPRINTS
• RISK
• STATISTICAL ANALYSIS

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE