Accession Number:

ADA562937

Title:

Ultraviolet B Irradiance and Vitamin D Status are Inversely Associated With Incidence Rates of Pancreatic Cancer Worldwide

Descriptive Note:

Journal article

Corporate Author:

NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA

Personal Author(s):

• Mohr, Sharif B.
• Garland, Cedric F.
• Gorham, Edward D.
• Grant, William B.
• Garland, Frank C.

Report Date:

2010-01-01

Pagination or Media Count:

8.0

Abstract:

Approximately 232,000 new cases and 227,000 deaths occur worldwide annually from pancreatic cancer, including 37,700 cases and 34,200 deaths in the US alone. The possibility that Vitamin D might play a role in the etiology of pancreatic cancer was raised by studies showing that populations living at higher latitudes, or having lower prediagnostic serum 25-hydroxyvitamin D 25OHD levels, have higher incidence rates of various cancers. Countries with lower UVB irradiance had higher incidence rates of pancreatic cancer in both hemispheres, with occasional exceptions.

Descriptors:

• *PANCREATIC DISEASES
• *VITAMIN D
• ALCOHOLS
• BLOOD SERUM
• LATITUDE
• POPULATION
• REPRINTS
• TOBACCO SMOKING
• ULTRAVIOLET RADIATION

Subject Categories:

• Biochemistry
• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE