DID YOU KNOW? DTIC has over 3.5 million final reports on DoD funded research, development, test, and evaluation activities available to our registered users. Click
HERE to register or log in.
Accession Number:
ADA561593
Title:
Adenovirus 36 Seropositivity is Strongly Associated With Race and Gender, But Not Obesity, Among U.S. Military Personnel
Descriptive Note:
Journal article
Corporate Author:
NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA
Report Date:
2010-01-01
Pagination or Media Count:
10.0
Abstract:
Background. Several studies have shown a positive association between evidence of anti-Adenovirus 36 Ad-36 antibodies Ad-36 exposure and 1 obesity and 2 serum cholesterol in animals. There is limited research on 1 demonstrating this association in humans and 2 transmission, presentation, and demographics of Ad-36 infection. Design 1 Body mass, 2 fasting serum cholesteroltriglyceride levels, 3 and demographic characteristics were compared between Ad-36 seropositive and seronegative groups. Subjects One hundred fifty obese and 150 lean active-duty military personnel were studied. Measurements Subjects completed a questionnaire regarding demographicbehavioral characteristics. Subject serum samples were tested by neutralization assay for presence of Ad-36 antibodies. Results Thirty-four percent of obese and 39 of lean subjects had Ad-36 exposure, an insignificant difference. Cholesteroltriglyceride levels were significantly higher among obese subjects than among lean, but there were no associations between cholesteroltriglyceride levels and Ad-36 exposure. Positive associations were found between Ad-36 exposure and age, race, and gender. Conclusion The study stands in contrast to previous work that has shown a positive relationship between Ad-36 exposure and 1 obesity and 2 levels of cholesterol and triglycerides. There was no association in either case. Unanticipated relationships between Ad-36 exposure and age, race, and gender were found.
Distribution Statement:
APPROVED FOR PUBLIC RELEASE
