Accession Number:

ADA558986

Title:

The Impact of Hazardous Chemicals on Macrophages

Descriptive Note:

Final technical rept.

Corporate Author:

OKLAHOMA UNIV OKLAHOMA CITY

Personal Author(s):

• Ballard, Jimmy
• Regens, James

Report Date:

2012-04-01

Pagination or Media Count:

32.0

Abstract:

The goals of this study were to identify the impact of hazardous chemicals on macrophages, determine how the macrophages respond to these chemicals, and use these signatures to develop novel detection technologies. As a model for this system we selected toxic industrial chemicals and used mouse macrophages as the target cell type.

Descriptors:

• *CHEMICALS
• *HAZARDOUS MATERIALS
• *MACROPHAGES
• *TOXICITY
• CELLS
• CHEMICAL WARFARE AGENTS
• DETECTION
• IMPACT
• INDUSTRIES
• INFLAMMATION
• INHALATION
• MICE
• MODELS
• RESPIRATORY DISEASES
• RESPONSE(BIOLOGY)
• SENSE ORGANS
• TARGETS
• WATER TREATMENT

Subject Categories:

• Toxicology
• Industrial Chemistry and Chemical Processing

Distribution Statement:

APPROVED FOR PUBLIC RELEASE