Accession Number:

ADA558870

Title:

Breast Cancer Endothelial Cell Calcium Dynamics Using Two-Photon Microscopy

Descriptive Note:

Annual summary rept. 1 Jan-31 Dec 2011

Corporate Author:

ROCHESTER UNIV NY

Personal Author(s):

Report Date:

2012-01-01

Pagination or Media Count:

10.0

Abstract:

Control murine liver endothelial cells and murine breast tumor endothelial cells were successfully isolated and plated for the imaging and flow cytometry experiments. I have found interesting differences between normal and tumor endothelial cells well worth further studying. More specifically, I have found that the response of tumor endothelial cells to VEGF is the same regardless of whether or not they have been serum-starved. Also receptor densities of VEGFR-1 and -2 differ between normal and breast tumor ECs.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE