Accession Number:

ADA556904

Title:

Label Structured Cell Proliferation Models

Descriptive Note:

Technical rept.

Corporate Author:

NORTH CAROLINA STATE UNIV AT RALEIGH CENTER FOR RESEARCH IN SCIENTIFIC COMPUTATION

Personal Author(s):

• Banks, H. T.
• Charles, Frederique
• Jauffret, Marie D.
• Sutton, Karyn L.
• Thompson, W. C.

Report Date:

2010-06-16

Pagination or Media Count:

7.0

Abstract:

We present a general class of cell population models that can be used to track the proliferation of cells which have been labeled with a fluorescent dye. The mathematical models employ fluorescence intensity as a structure variable to describe the evolution in time of the population density of proliferating cells. While cell division is a major component of changes in cellular fluorescence intensity, models developed here also address overall label degradation.

Descriptors:

• *CELL DIVISION
• *MATHEMATICAL MODELS
• PARTIAL DIFFERENTIAL EQUATIONS

Subject Categories:

• Biology
• Microbiology
• Operations Research
• Test Facilities, Equipment and Methods

Distribution Statement:

APPROVED FOR PUBLIC RELEASE