Accession Number:

ADA555840

Title:

Exploring the Mechanism of Biomolecule Immobilization on Plasma-Treated Polymer Substrates

Descriptive Note:

Book chapter

Corporate Author:

NAVAL RESEARCH LAB WASHINGTON DC

Report Date:

2012-01-01

Pagination or Media Count:

9.0

Abstract:

An electron beam-generated plasma source developed at NRL was used to modify polystyrene microtitre plates. A combination of complementary surface analytical and biochemical techniques was applied to evaluate the relationship between the biotic and abiotic layers, with particular emphasis on the efficiency of the preparation of polymer surfaces and its effectiveness for bioimmobilization. We conclude that the development of novel interface materials with superior transducing capabilities is dependent on the deeper understanding of the complex physicochemical, nanoscale interactions between the substrate surface and the biological components attached to it.

Subject Categories:

  • Biochemistry
  • Plastics
  • Plasma Physics and Magnetohydrodynamics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE