Accession Number:

ADA555154

Title:

Etiology of Acute, Non-Malaria, Febrile Illnesses in Jayapura, Northeastern Papua, Indonesia

Descriptive Note:

Journal article

Corporate Author:

NAVAL MEDICAL RESEARCH UNIT NO 2 DETACHMENT JAKARTA (INDONESIA)

Report Date:

2012-01-01

Pagination or Media Count:

7.0

Abstract:

We conducted a prospective, inpatient fever study in malaria-endemic Papua, Indonesia to determine nonmalaria fever etiologies. Investigations included malaria blood films, blood culture, paired serologic samples analysis for dengue, Japanese encephalitis, leptospirosis, scrub typhus, murine typhus, and spotted fever group rickettsia. During 1997 2000, 226 patients 127 males and 99 females 1 80 years of age median age 25 years were enrolled. Positive blood cultures n 34, 15 were obtained for Salmonella Typhi n 13, Escherichia coli n 8, Streptococcus pneumoniae n 6, Staphylococcus aureus n 5, Streptococcus pyogenes n 1, and Klebsiella pneumoniae n 1. Twenty 8.8 patients were positive for leptospirosis by polymerase chain reaction. Eighty 35.4 of 226 patients had 1 positive serology, diagnostic for 15 rickettsial and 9 dengue cases. Acid-fast bacilli positive sputum was obtained from three patients. Most common confirmed 81 of 226, 35.8suspected diagnoses were typhoid fever n 41, pneumonia n 29, leptospirosis n 28, urinary tract infections n 20, rickettsioses n 19, dengue n 17, and meningitisencephalitis n 15. There were 17 deaths, 7 46.7 were caused by meningitisencephalitis. Multiple positive serologic results and few confirmed diagnoses indicate the need for improved diagnostics.

Subject Categories:

  • Medicine and Medical Research
  • Ecology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE