Sulfadoxine-Pyrimethamine-Based Intermittent Preventive Treatment, Bed Net Use, and Antenatal Care during Pregnancy: Demographic Trends and Impact on the Health of Newborns in the Kassena Nankana District, Northeastern Ghana
NAVAL MEDICAL RESEARCH CENTER SILVER SPRING MD
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Demographics and health practices of 2,232 pregnant women in rural northeastern Ghana and characteristics of their 2,279 newborns were analyzed to determine benefits associated with intermittent preventive treatment IPTp , antenatal care, andor bed net use during pregnancy. More than half reported bed net use, 90 reported at least two antenatal care visits, and 82 took at least one IPTp dose of sulfadoxine-pyrimethamine. Most used a bed net and IPTp 45 or IPTp alone 38.Lowbirth weight 2,500 grams characterized 18.3 of the newborns and was significantly associated with female sex, Nankam ethnicity, first-born status, and multiple births. Among newborns of primigravidae IPTp was associated with a significantly greater birth weight, significantly fewer low birth weight newborns, improved hemoglobin levels, and less anemia. Babies of multigravidae derived no benefit to birth weight or hemoglobin level from single or multiple doses of sulfadoxine-pyrimethamine during pregnancy. No differences or benefits were seen when a bed net was the only protective factor.
- Anatomy and Physiology
- Medicine and Medical Research