Accession Number:

ADA547526

Title:

Microsporidiosis

Descriptive Note:

Corporate Author:

RUTGERS - THE STATE UNIV NEWARK NJ

Report Date:

2011-06-01

Pagination or Media Count:

25.0

Abstract:

Definition Microsporidiosis is infection by eukaryotic unicellular protists of the phylum Microsporidia. They are considered most closely related to the fungi, but customarily are discussed among the protozoa. Several genera of microsporidia have been identified in human infections Nosema, Brachiola, Vittaforma, Pleistophora, Trachipleistophora, Enterocytozoon, Encephalitozoon, Septata, and Anncaliia All microsporidia are obligate intracellular parasites, but pathologic changes vary with genus and species. In humans, infection may be latent or subclinical until the immune system is suppressed. Microsporidia are a significant opportunistic pathogen in patients with AIDS. Clinical features vary with the location and extent of infection. Microsporidia may infect virtually any tissue or organ of the body, including muscle, intestine, gallbladder, liver, kidneys, eyes, brain, lungs, skin, and nasal sinuses. Intestinal microsporidiosis is most common, occurring in 30 to 50 of AIDS patients with chronic diarrhea. Untreated intestinal, renal, cerebral, hepatic and disseminated infections are usually fatal.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE