A Multimodality Ultramicrospectroscope (MUMS): Nanoscale Imaging with Integrated Spectroscopies for Chemical and Biomolecular Identification
Final rept. 1 Jun 2004-30 Nov 2009
RICE UNIV HOUSTON TX
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The goals of this MURI were to develop the next generation suite of instruments for sensitively probe biomolecules of interest. We have very successfully pursued plasmon based nanostructures as substrates to enhance various optical spectroscopies such as surface enhanced Raman spectroscopy, surface enhanced infra red absorption, metal enhanced fluorescence, surface enhanced Raman optical activity and LSPR sensing. We have developed a complete theoretical understanding of the electromagnetic field enhancement using Plasmon Hybridization, FDTD, FEM, along with rigorous analytical and quantum mechanical calculations. This has been applied to rationally design and optimize the substrates. The Plasmon Hybridization theory is now a well accepted approach to understanding plasmons in complex and coupled systems. We have developed the first near infra red ROA spectrometer and used it to obtain the first NIR excited ROA spectra. This has also lead to the funding of two STTRs and collaborations with Biotools, the only company selling a commercial ROA spectrometer. Finally we have developed the plasmonic equivalent of coherent phenomenon electromagnetically induced transparency, sub- and superradiant modes, and Fano resonances, previously observed only in atomic systems. Nanostructures that have a Fano resonance have been demonstrated to have some of the highest LSPR sensitivity reported.
- Atomic and Molecular Physics and Spectroscopy