Accession Number:

ADA539083

Title:

Topical Treatment of Cutaneous Leishmaniasis W/WR279396 Phase II Study

Descriptive Note:

Addendum to final rept. for 1 Apr 2006-31 Mar 2007

Corporate Author:

PASTEUR INSTITUTE TUNIS (TUNISIA)

Personal Author(s):

Report Date:

2007-05-01

Pagination or Media Count:

20.0

Abstract:

A second phase 2 clinical study was performed in the Tunisian site to determine a the efficacy and safety of WR279396 administered once a day for 20 days vs twice a day for 20 days b if WR279396 applied under a polyurethane occlusive bandage Tegaderm tm is more active than application of the drug without occlusion and c the extend of parasite load reduction after a daily application of WR279396. The study started in January 06 and terminated in February 07. Forty eight 48 patients were included. The preliminary results confirmed the efficacy of the WR279396 in the treatment of the Old World CL. During this reporting period, a two Phase III studies in Old World Tunisia and in New World French Guyana are being planned.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE