A Randomized Controlled Trial of Medical Therapies for Chronic Post-Traumatic Headaches
Annual rept. 1 May 2009-30 Apr 2010
HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE ROCKVILLE MD
Pagination or Media Count:
A randomized, placebo-controlled clinical trial is being conducted to evaluate the effectiveness of propranolol, topiramate, and amitriptyline as treatments for chronic post-traumatic headaches secondary to combat-related mild head injury. The study is in the first of three years. 34 of 240 subjects have been enrolled. The study medications are well tolerated. Study subjects had a 60 decrease in headache frequency after 3 months of treatment. There is insufficient data at this time to draw conclusions about the efficacy of specific study medications. The study remains open to enrollment.
- Medicine and Medical Research
- Military Forces and Organizations