Accession Number:

ADA535889

Title:

A Randomized Controlled Trial of Medical Therapies for Chronic Post-Traumatic Headaches

Descriptive Note:

Annual rept. 1 May 2009-30 Apr 2010

Corporate Author:

HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE ROCKVILLE MD

Personal Author(s):

Report Date:

2010-05-01

Pagination or Media Count:

6.0

Abstract:

A randomized, placebo-controlled clinical trial is being conducted to evaluate the effectiveness of propranolol, topiramate, and amitriptyline as treatments for chronic post-traumatic headaches secondary to combat-related mild head injury. The study is in the first of three years. 34 of 240 subjects have been enrolled. The study medications are well tolerated. Study subjects had a 60 decrease in headache frequency after 3 months of treatment. There is insufficient data at this time to draw conclusions about the efficacy of specific study medications. The study remains open to enrollment.

Subject Categories:

  • Medicine and Medical Research
  • Military Forces and Organizations

Distribution Statement:

APPROVED FOR PUBLIC RELEASE