Accession Number:

ADA528824

Title:

Treatment of Hepatitis C Infections with Interferon: A Historical Perspective

Descriptive Note:

Corporate Author:

UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD DEPT OF PATHOLOGY

Personal Author(s):

Report Date:

2010-01-01

Pagination or Media Count:

5.0

Abstract:

Interferons were first described in 1957, but it was not until 34 years after their discovery that sufficient quantities of it were available for treatment of hepatitis C virus HCV infections, Clinicians now have an excellent understanding of the basis for the effectiveness of interferon alpha IFN-alpha in the therapy of this disease. Treatment with IFN-alpha is more efficient when it complemented by the antiviral ribavirin and the IFN-alpha is conjugated with polyethylene glycol to form peginterferon. In the near future treatment of HCV with IFN-alpha may involve new anti-HCV agents that are currently under development.

Subject Categories:

  • Sociology and Law
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE