Accession Number:

ADA525608

Title:

Role of Fibroblast Growth Factor Binding Protein-1 in Mammary Development and Tumorigenesis

Descriptive Note:

Annual rept. 15 Sep 2006-14 Sep 2009

Corporate Author:

GEORGETOWN UNIV WASHINGTON DC MEDICAL CENTER

Personal Author(s):

Report Date:

2009-10-01

Pagination or Media Count:

14.0

Abstract:

Fibroblast growth factors FGFs are vital modulators of development as well as angiogenesis. They play a large role in vascular formation, body axis patterning, cell migration and organ branching. The scientific community is still piecing together the role that distinct FGFs play due to the complexity of the FGF network, which involves 22 distinct members that signal through 4 receptors to activate 3 major signaling pathways.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE