Accession Number:

ADA525085

Title:

Dietary Heterocyclic Amines and Polymorphic Variants in the Etiology of Prostate Cancer

Descriptive Note:

Final rept. 15 Dec 2004-31 Dec 2009

Corporate Author:

OTTAWA UNIV (ONTARIO)

Personal Author(s):

Report Date:

2010-01-01

Pagination or Media Count:

27.0

Abstract:

This project explored the hypothesis that higher intake of dietary carcinogens e.g. heterocyclic amines was associated with elevated risk of prostate cancer. It also explored the potential that polymorphic variation in key metabolism genes may affect risk. The project conducted a case-control study on 392 cases and 342 controls. Biosamples were obtained on over 96 of participants. Initial analyses provide only limited support for our hypothesis, mostly trends without clear statistical significance.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Food, Food Service and Nutrition

Distribution Statement:

APPROVED FOR PUBLIC RELEASE