Accession Number:

ADA516728

Title:

Capillary Inlet Concentrator for the Integrated Virus Detection System (IVDS)

Descriptive Note:

Final rept. Oct 2004-Jul 2005

Corporate Author:

EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR

Personal Author(s):

• Wick, Charles H.
• McCubbin, Patrick E.

Report Date:

2010-03-01

Pagination or Media Count:

12.0

Abstract:

The standard method for concentration of virus samples with the Integrated Vims Detection System IVDS is to use a tangential flow filtration system to reduce the volume of the sample, while removing impurities such as salts and small cellular debris. This report investigated the IVDS ability to concentrate the virus sample as well as remove impurities with a filtration attachment on the inlet side of the electrospray module. The filtration attachment or concentrator allowed the virus sample to be purified and concentrated and then analyzed with the IVDS without removing the sample from the IVDS.

Descriptors:

• *DETECTION
• *VIRUSES
• BIOLOGICAL AGENTS
• DEBRIS
• CELLS
• FILTRATION
• PARTICLES
• CONCENTRATION(COMPOSITION)
• INLETS
• CAPILLARITY
• CONDENSATION
• MOBILITY
• INJECTION
• IMPURITIES

Subject Categories:

• Microbiology
• Chemical, Biological and Radiological Warfare

Distribution Statement:

APPROVED FOR PUBLIC RELEASE