AFSOR Bio-X: Encapsulated DNA-Based Molecular Autonomous Sensing Devices With Photonic I/O
Final rept. 4 Jan 2008-3 Jan 2009
DUKE UNIV DURHAM NC DEPT OF COMPUTER SCIENCE
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Purpose of this program was DNA-based nanostructure detector system development and demonstration with multispectral optical readouts. The overarching goal of this research was the remote hyperspectral detection of molecular targets, with application as a combat ready, modular, general purpose target detection and signal amplification system coupled to airborne imaging systems. The specific Tasks of this project were 1 To develop systems that amplify detection events through the use of existing biomolecular amplification methods 2 To optimize hydrogelaerogel encapsulation and preservation of the biomolecular detection systems to ensure robust activity upon rehydration in the field 3 To demonstrate remote detection by such systems using hyperspectral imaging.
- Genetic Engineering and Molecular Biology
- Atomic and Molecular Physics and Spectroscopy