Accession Number:

ADA513574

Title:

Serum Ropivacaine Concentrations and Systemic Local Anesthetic Toxicity in Trauma Patients Receiving Long-Term Continuous Peripheral Nerve Block Catheters

Descriptive Note:

Journal article

Corporate Author:

WALTER REED ARMY INST OF RESEARCH WASHINGTON DC DIV OF SURGERY

Report Date:

2010-02-01

Pagination or Media Count:

6.0

Abstract:

Ropivacaine is a long-acting local anesthetic used frequently for peripheral nerve blocks and continuous peripheral nerve block catheters. Combat trauma patients at Walter Reed Army Medical Center often receive continuous peripheral nerve block catheters as part of their pain regimen. These catheters remain in situ for several days to weeks. In this study, we evaluated the free ropivacaine drug levels over time in trauma patients by measuring the serum concentration of bound and unbound local anesthetic. The corresponding 1-acid glycoprotein concentration in patients with prolonged ropivacaine infusions was also measured.

Subject Categories:

  • Medicine and Medical Research
  • Medical Facilities, Equipment and Supplies

Distribution Statement:

APPROVED FOR PUBLIC RELEASE