NCCU/BBRI-Duke/Urology Partnership in Prostate Cancer Research
Annual rept. 18 May 2008-17 May 2009
NORTH CAROLINA CENTRAL UNIV DURHAM
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The NCCUBBRI-DukeUrology Partnership in Prostate Cancer Research was developed to promote Collaborative Training, Research, and Community Dialogue and Outreach among scientists from NCCU and Duke. During the second funding period, we have first received full approval of our IACUC protocol and recently our IRB. We are now breeding the mouse model of prostate cancer deficient in betaarrestin 2 TRAMP-betaarr2-- to further determine the role of betaarr2 in prostate tumor development. We are also developing TRAMP-Alox5-- mouse model to address the questions posed in project 3. The accrual of prostatic samples at Duke-VA has also started and processed samples will be made available to NCCU scientists for analysis as soon as significant numbers of cases and controls are collected. Three manuscripts directly related with the NCCUBBRI-DukeUrology Partnership have been submitted. One has been accepted and two are currently under revisions. The collaborative efforts have also led to the submission of 9 grant proposals with NCCU scientist as principal investigators. Unfortunately, the U54 application in partnership with UNC-Lineberger and Duke Comprehensive Cancer Centers entitled NCCU-DCCC-LCCC Partnership In Cancer Research was not funded. We are currently reviewing the proposal for a later submission.
- Medicine and Medical Research