Accession Number:

ADA509950

Title:

A Partnership Training Program in Breast Cancer Research Using Molecular Imaging Techniques

Descriptive Note:

Annual rept. 1 Jul 2007-30 Jun 2008

Corporate Author:

HOWARD UNIV WASHINGTON DC

Personal Author(s):

Report Date:

2008-07-01

Pagination or Media Count:

113.0

Abstract:

In the third year, Howard faculty from Departments of Biology, Radiology, and Radiation Oncology at Howard University were further trained in molecular imaging through seminars and workshops, and by conducting two research projects with the faculty at the Johns Hopkins University. We have established three breast cancer tumor models, and further optimized the imaging probes for MRI and fluorescent optical imaging of breast cancers. We have determined how the interactions between MCF-7 cells and macrophages are affected by tamoxifen and aspirin. We have also identified the phenotypic changes that may render TAMs selectively vulnerable to pharmacological agents. In this report period, we have published 11 papers and given 24 presentations. Based on the data we obtained, we have submitted 5 new grant proposals to NIH and DoD. The Molecular Imaging Lab continuously serves as a synergic center on campus to promote molecular imaging research. Six new research collaborations were established with the faculty members at Howard, as well as with the scientists from other institutes.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE