Cone-Beam Computed Tomography for Image-Guided Radiation Therapy of Prostate Cancer
Annual summary 11 Dec 2007-11 Dec 2008
CHICAGO UNIV IL
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The success of intensity-modulated radiation therapy IMRT or 4-D conformal radiation therapy CRT is heavily reliant on accurate image-guidance in prostate cancer treatment. Cone-beam computed tomography CBCT is becoming one of the dominant imaging modalities for image-guidance, but current technology based on Feldkamp algorithm for image reconstruction from a circular scanning trajectory does not yield sufficient quality of images. In addition, imaging-radiation dose is one of the key issues, which has to be minimized or optimized. We report our continued research on CBCT scanning methods and corresponding image reconstruction algorithms that can increase the accuracy of the images andor reduce patient dose from CBCT. A BPF-FBP tandem algorithm for reverse helical CBCT has been developed, intensity-weighted region-of-interest image reconstruction methods have been explored, and a prior-image-based few-view CBCT approach has been proposed.
- Anatomy and Physiology
- Medicine and Medical Research
- Computer Programming and Software