Accession Number:

ADA506214

Title:

Medical Surveillance Monthly Report. Volume 16, Number 7, July 2009

Descriptive Note:

Monthly rept.

Corporate Author:

ARMED FORCES HEALTH SURVEILLANCE CENTER SILVER SPRING MD

Personal Author(s):

Report Date:

2009-07-01

Pagination or Media Count:

21.0

Abstract:

Lyme disease is a zoonotic tick-borne disease that is caused by infection with a spirochetal bacterium of the genus Borrelia. It has a worldwide distribution and is endemic in many temperate regions of the northern hemisphere. In the United States, it is hyperendemic along the mid- and northeastern Atlantic seaboard and in nonurban areas of Wisconsin. Lyme disease is transmitted by ticks that feed on both humans and animal hosts of Borrelia e.g., deer, mice, raccoons. Borrelia are usually transmitted to humans during blood meals of ticks in the nymphal stages of their life cycle. Nymphal stage ticks are very small approximately the size of poppyseeds hence, they often feed undetected for the time required to transmit infection 24-48 hours. In the United States, the deer tick Ixodes scapularis and western blacklegged tick Ixodes pacificus are competent vectors of Lyme disease. The clinical manifestations and courses of Lyme disease are highly variable. The time from infection to initial symptoms is generally 7-14 days range 3 to 30 days. The presenting manifestation of Lyme disease is often a slowly enlarging, centrally clearing bulls-eye rash at the site of the infecting tick bite erythema migrans. While erythema migrans is a distinctive characteristic of Lyme disease, it occurs in only 60-80 of cases. Other early manifestations are non-specific and include fever, headache, muscle aches, joint pains, lymphadenopathy, malaise, and fatigue. Without effective antibiotic treatment, acute symptoms can persist for weeks or more. Weeks to months after infection, clinical manifestations of inflammation of the joints, nervous system e.g., facial palsy, encephalitis, and heart e.g. conduction abnormalities can occur. Most cases are effectively treated with single courses of antibiotics.

Subject Categories:

  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE