Accession Number:

ADA505794

Title:

An Environmental Sentinel Biomonitor System for Drinking Water Protection

Descriptive Note:

Conference paper

Corporate Author:

ARMY CENTER FOR ENVIRONMENTAL HEALTH RESEARCH FORT DETRICK MD

Personal Author(s):

• Widder, M. W.
• Trader, D.
• Brennan, L.
• Shedd, T. R.
• Gargan, II, T. P.
• van der Schalie, W. H.
• Salazar, N.
• Vallejo, Y. R.

Report Date:

2008-12-01

Pagination or Media Count:

7.0

Abstract:

Toxic industrial chemicals TICs are a potential threat to field drinking water supplies, but capabilities for rapid field testing of water are limited to relatively few chemicals. The Environmental Sentinel Biomonitor ESB system will significantly augment current detection methods by rapidly identifying toxicity from chemicals that currently cannot be rapidly detected in water samples in the field. The ESB system utilizes two toxicity sensors - a cell based electrical impedance sensor and an enzyme based acetylcholinesterase AChE inhibition sensor - to rapidly respond to a wide range of TICs. Future improvements to the ESB system under evaluation include the use of non-mammalian vertebrate cells to improve sensitivity and reduce logistical requirements and the development of an AChE inhibition sensor to provide more rapid detection with fewer steps and reagents.

Descriptors:

• *TOXICITY
• *ACETYLCHOLINESTERASE
• *DRINKING WATER
• FIELD TESTS
• WATER SUPPLIES
• PROTECTION
• RANGE(EXTREMES)
• ACCELERATED TESTING
• FIELD CONDITIONS
• CHEMICALS
• INDUSTRIES
• QUICK REACTION
• SAMPLING

Subject Categories:

• Biochemistry
• Toxicology
• Physical and Dynamic Oceanography
• Water Pollution and Control

Distribution Statement:

APPROVED FOR PUBLIC RELEASE