Accession Number:

ADA505736

Title:

Allograft Fascia Lata as an Augmentation Device for Musculoskeletal Repairs

Descriptive Note:

Conference paper

Corporate Author:

CLEVELAND CLINIC FOUNDATION OH

Personal Author(s):

• Derwin, K. A.
• Aurora, A.
• Iannotti, J. P.

Report Date:

2008-12-01

Pagination or Media Count:

7.0

Abstract:

Musculoskeletal soft tissue injuries during combat are a source of debilitating pain, the treatment and evaluation of which pose a significant challenge to the orthopedic community. Extracellular matrix ECM scaffolds derived from various sources and species are being explored for the repair of musculoskeletal tendon injuries. In this paper we demonstrate that amongst these ECM scaffolds, only tensor fascia lata has structural and tensile material properties comparable to tendon, but fascia has poor suture retention properties. We have devised a novel means to increase the suture retention properties of fascia lata by developing a composite of the ECM tissue and biodegradable polymers. This technique may facilitate the efficacious use of fascia lata in the area of regenerative medicine, particularly for musculoskeletal repairs.

Descriptors:

• *MUSCULOSKELETAL SYSTEM
• *ELECTRONIC COUNTERMEASURES
• *AUGMENTATION
• *REPAIR
• *FASCIA
• MEDICINE
• HETEROGENEITY
• WOUNDS AND INJURIES
• TENSORS
• PAIN
• RETENTION(PSYCHOLOGY)
• CONSTRUCTION MATERIALS
• REGENERATION(ENGINEERING)
• SOFT TISSUES
• BIODETERIORATION
• SURGICAL TRANSPLANTATION
• TENSILE PROPERTIES
• POLYMERS
• STRUCTURAL PROPERTIES
• ORTHOPEDICS
• TISSUES(BIOLOGY)
• COMMUNITIES

Subject Categories:

• Anatomy and Physiology
• Medicine and Medical Research
• Optical Detection and Detectors

Distribution Statement:

APPROVED FOR PUBLIC RELEASE